Candidemia isolates, identification and antifungal susceptibility testing: a study from a tertiary care centre


Author Details : Linda Rose Jose, Jayanthi Savio

Volume : 4, Issue : 4, Year : 2017

Article Page : 464-467


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Abstract

Aim: This study is aimed to characterize the epidemiology and antifungal susceptibility profile of Candida isolates from candidemia cases in a tertiary care centre in both ICU and non- ICU patients.
Materials and Method: This study was conducted in Department of Microbiology, St. John’s Medical College and Hospital, Bangalore for a period of 6 months. Ethical approval was obtained from the Institutional Ethics Committee. Blood culture bottles from the adult and paediatric wards were incubated for a period of 7 days at 370C.Once the blood cultures showed growth, further processing was done. The Candida isolates were speciated using conventional morphological and biochemical tests.
Results: C.tropicalis was the predominant isolate accounting for 53.3% out of the 30 Candida isolates obtained during this study period. The incidence of candidemia was higher in ICU patients(77%). An emerging drug resistance to Fluconazole was observed among C.albicans.
Conclusion: The frequency of candidemia among hospitalized patients has increased greatly during the recent years.

Keywords: Candidemia, Candida, Antifungal susceptibility testing, C.tropicalis

 


How to cite : Jose L R, Savio J, Candidemia isolates, identification and antifungal susceptibility testing: a study from a tertiary care centre. Indian J Microbiol Res 2017;4(4):464-467


Copyright © 2017 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)



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